Inter head into their fixture with Atalanta looking for a first victory over Stefano Colantuono's side since April 2010.
The Milan outfit suffered two defeats to Atalanta last season, including a thrilling 4-3 reverse at San Siro in April, and drew both meetings in the 2011-12 campaign.
Their last success came in a 3-1 home win more than three years ago, with goals from Diego Milito, Sulley Muntari and Christian Chivu securing the points on that occasion.
Inter go into Tuesday's game at the Stadio Atleti Azzurri d'Italia on the back of a 4-2 home victory over Verona.
That triumph ended a run of three Serie A matches without a win for Walter Mazzarri's side, and left them fourth with 18 points from nine games.
Ishak Belfodil is absent through suspension for Inter following his sending-off after the final whistle against Verona.
Atalanta have struggled for consistency so far in Serie A, but occupy a respectable position of ninth with 12 points to their name.